Abstract--The 3rd Generation Partnership Project (3GPP), the standards body for mobile networks, is in the final phase of Release 19 standardization and is beginning Release 20. Artificial Intelligence/ Machine Learning (AI/ML) has brought about a paradigm shift in technology and it is being adopted across industries and verticals. This paper focuses on the AI/ML related technological advancements and features introduced in Release 19 within the Service and System Aspects (SA) T echnical specifications group of 3GPP . The advancements relate to two paradigms: (i) enhancements that AI/ML brought to the 5G advanced system (AI for network), e.g. Artificial Intelligence (AI) and Machine Learning (ML) are transforming numerous industries and multiple aspects of modern life. From personalized recommendations on streaming platforms to real-time fraud detection in banking, AI/ML technologies are driving smarter decision-making across industries. In retail, they assist in inventory and supply chain management. In transportation, automotive vehicles rely on ML for object detection and navigation. As data continues to grow, these technologies are evolving rapidly, reshaping how we work, interact, and solve complex problems, making them central to innovation in today's world.

Randomized controlled trials (RCTs) have been the cornerstone of clinical evidence; however, their cost, duration, and restrictive eligibility criteria limit power and external validity. Studies using real-world data (RWD), historically considered less reliable for establishing causality, are now recognized to be important for generating real-world evidence (RWE). In parallel, artificial intelligence and machine learning (AI/ML) are being increasingly used throughout the drug development process, providing scalability and flexibility but also presenting challenges in interpretability and rigor that traditional statistics do not face. This Perspective argues that the future of evidence generation will not depend on RCTs versus RWD, or statistics versus AI/ML, but on their principled integration. To this end, a causal roadmap is needed to clarify inferential goals, make assumptions explicit, and ensure transparency about tradeoffs. We highlight key objectives of integrative evidence synthesis, including transporting RCT results to broader populations, embedding AI-assisted analyses within RCTs, designing hybrid controlled trials, and extending short-term RCTs with long-term RWD. We also outline future directions in privacy-preserving analytics, uncertainty quantification, and small-sample methods. By uniting statistical rigor with AI/ML innovation, integrative approaches can produce robust, transparent, and policy-relevant evidence, making them a key component of modern regulatory science.

Applications of artificial intelligence or machine learning in research Modes of use Surrogate modeling for physics - based models Modeling of poorly understood phenomena Data preprocessing Large language model use Applications AI/ML as research tool Production process design, monitoring, & output prediction Part design & properties prediction Materials design & properties prediction AI/ML as research product Generative AI design tool for consumers Generic research tasks Large language models for coding Large language models for literature review Benefits of artificial intelligence or machine learning in research Reduction in accuracy/cost/speed trade - off in research, especially computer modeling Reduced computation time Replacing experimentation Reducing need for computationally intensive, physics - based models Saving research labor Exploring larger design spaces Address of previously unsolvable problems Model poorly understood relationships between variables Identify human - unidentifiable patterns or phenomena Downsides of artificial intelligence or machine learning in research Accuracy weaknesses Predict poorly outside regions of dense, high - quality training data Interpretability weaknesses Bounds of accuracy can be unclear Accuracy assessment can be difficult Long - run scientific progress concerns AI/ML cannot develop novel scientific theory AI/ML may bypass opportunities to identify empirical or theoretical novelties Resource issues Data acquisition and cleaning is time - intensive AI/ML models are computation - and energy - intensive to develop Inappropriate use issues Easy to over - trust May be inappropriately used to address problems soluble with simpler methods 8 Second, AI/ML models can be trained on input and output data for phenomena (e.g., complex production processes) which lack robust theoretical models, developing novel predictive capabilities in the absence of explicit, human - designed theory. This is somet imes referred to as "phenomenological modeling," as it attempts to model phenomena in the absence of mechanistic, explanatory understanding: [T]he first reason we choose to use AI is because we don't have a good model of what our system is. . . I get a bunch of data coming in and I have a bunch of sensor readings, you know. . . And I use the AI to map the bunch of sensor readings to the process health or process status or machine status that I have.

Course syllabi set the tone and expectations for courses, shaping the learning experience for both students and instructors. In computing courses, especially those addressing fairness and ethics in artificial intelligence (AI), machine learning (ML), and algorithmic design it is imperative that we understand how approaches to navigating barriers to fair outcomes are being addressed.These expectations should be inclusive, transparent, and grounded in promoting critical thinking. Syllabus analysis offers a way to evaluate the coverage, depth, practices, and expectations within a course. Manual syllabus evaluation, however, is time-consuming and prone to inconsistency. To address this, we developed a justice-oriented scoring rubric and asked a large language model (LLM) to review syllabi through a multi-perspective role simulation. Using this rubric, we evaluated 24 syllabi from four perspectives: instructor, departmental chair, institutional reviewer, and external evaluator. We also prompted the LLM to identify thematic trends across the courses. Findings show that multi-perspective evaluation aids us in noting nuanced, role-specific priorities, leveraging them to fill hidden gaps in curricula design of AI/ML and related computing courses focused on fairness and ethics. These insights offer concrete directions for improving the design and delivery of fairness, ethics, and justice content in such courses.

AI/ML research has predominantly been driven by domains such as computer vision, natural language processing, and video analysis. In contrast, the application of AI/ML to wireless networks, particularly at the air interface, remains in its early stages. Although there are emerging efforts to explore this intersection, fully realizing the potential of AI/ML in wireless communications requires a deep interdisciplinary understanding of both fields. We provide an overview of AI/ML-related discussions in 3GPP standardization, highlighting key use cases, architectural considerations, and technical requirements. We outline open research challenges and opportunities where academic and industrial communities can contribute to shaping the future of AI-enabled wireless systems.

Machine learning models deployed locally on social media applications are used for features, such as face filters which read faces in-real time, and they expose sensitive attributes to the apps. However, the deployment of machine learning models, e.g., when, where, and how they are used, in social media applications is opaque to users. We aim to address this inconsistency and investigate how social media user perceptions and behaviors change once exposed to these models. We conducted user studies (N=21) and found that participants were unaware to both what the models output and when the models were used in Instagram and TikTok, two major social media platforms. In response to being exposed to the models' functionality, we observed long term behavior changes in 8 participants. Our analysis uncovers the challenges and opportunities in providing transparency for machine learning models that interact with local user data.

Accurate localization in indoor environments is a challenge due to the Non Line of Sight (NLoS) nature of the signaling. In this paper, we explore the use of AI/ML techniques for positioning accuracy enhancement in Indoor Factory (InF) scenarios. The proposed neural network, which we term LocNet, is trained on measurements such as Channel Impulse Response (CIR) and Reference Signal Received Power (RSRP) from multiple Transmit Receive Points (TRPs). Simulation results show that when using measurements from 18 TRPs, LocNet achieves a 9 cm positioning accuracy at the 90th percentile. Additionally, we demonstrate that the same model generalizes effectively even when measurements from some TRPs randomly become unavailable. Lastly, we provide insights on the robustness of the trained model to the errors in ground truth labels used for training.

The Canadian fertilizer company Nutrien, for example, operates two dozen manufacturing and processing facilities spread across the globe and nearly 2,000 retail stores in the Americas and Australia. To collect underutilized data from its industrial operations, and gain greater visibility into its supply chain, the company relies on a combination of cloud technology and artificial intelligence/machine learning (AI/ML) capabilities. "A digital supply chain connects us from grower to manufacturer, providing visibility throughout the value chain," says Adam Lorenz, senior director for strategic fleet and indirect procurement at Nutrien. This visibility is critical when it comes to navigating the company's supply chain challenges, which include seasonal demands, weather dependencies, manufacturing capabilities, and product availability. The company requires real-time visibility into its fleets, for example, to identify the location of assets, see where products are moving, and determine inventory requirements.

This research looks at using AI/ML to achieve centimeter-level user positioning in 6G applications such as the Industrial Internet of Things (IIoT). Initial results show that our AI/ML-based method can estimate user positions with an accuracy of 17 cm in an indoor factory environment. In this proposal, we highlight our approaches and future directions.

Artificial intelligence (AI) and machine learning (ML) are nowadays mature technologies considered essential for driving the evolution of future communications systems. Simultaneously, Wi-Fi technology has constantly evolved over the past three decades and incorporated new features generation after generation, thus gaining in complexity. As such, researchers have observed that AI/ML functionalities may be required to address the upcoming Wi-Fi challenges that will be otherwise difficult to solve with traditional approaches. This paper discusses the role of AI/ML in current and future Wi-Fi networks and depicts the ways forward. A roadmap towards AI/ML-native Wi-Fi, key challenges, standardization efforts, and major enablers are also discussed. An exemplary use case is provided to showcase the potential of AI/ML in Wi-Fi at different adoption stages.